Since 2020, aggregated from related topics
AMP-activated protein kinase (AMPK) is a key regulator of cellular energy balance and metabolism. It is a serine/threonine protein kinase that is activated in response to low energy levels in the cell, such as during exercise or fasting. AMPK plays a central role in the regulation of glucose and lipid metabolism, as well as in the maintenance of cellular homeostasis. Research in the field of AMPK focuses on understanding its molecular mechanisms of action, its role in various disease states such as diabetes, obesity, and cancer, and the development of AMPK-targeted therapeutics for the treatment of these conditions. Additionally, studies are also investigating the potential of AMPK as a target for improving metabolic health, longevity, and overall well-being.